Peptides are hormone-like substances made by the brain and body to improve communication among cells, enhance learning, and promote mental clarity. They are used by individuals who have a medical condition such as Alzheimer’s, or traumatic brain injury, or those who have not yet developed these conditions but want to enhance their overall wellness and performance. They have become a popular supplement in many countries around the world due to their effectiveness.
A peptide called cerebrolysin is an FDA approved nootropic medication in some countries that has been shown to improve cognitive abilities and decrease symptoms of dementia, Alzheimer’s disease, Parkinson’s disease, and ALS. It is a parenteral liquid peptide preparation that contains a mixture of proteins and amino acids. It is available by prescription in the US and internationally.
The peptides in cerebrolysin reduce cellular damage caused by oxidative stress, regulate cell-signaling pathways, and stimulate neuroregeneration. They also increase synapse function and prevent amyloid deposition in the brain. It also decreases neocortical and hippocampal amyloid plaque load in transgenic mice overexpressing the APP gene. It has been found that cerebrolysin treatment significantly reduces behavioral and cognitive deficits of these mice up to 3 months after cessation of therapy.
Studies have demonstrated that high doses of cerebrolysin significantly reduces beta-amyloid deposits and slows the progression of Alzheimer’s disease. In addition, it improves psychological symptoms in patients with schizophrenia and helps to stabilize moods in people with depression, ADHD, and bipolar disorder. The treatment has been shown to be safe and well-tolerated.