GHK copper is a powerful and effective peptide that stimulates wound healing and has anti-inflammatory and tissue regenerative properties. It can be used to protect and regenerate tissues and organs such as the skin, stomach lining, intestinal lining, hair follicles and bone tissue.
It is also a very important factor in preventing and treating age related diseases such as osteoarthritis, rheumatoid arthritis and fibromyalgia. It has been shown to reduce oxidative stress, suppress production of ROS (reactive oxygen species), increase SOD and suppress pro-inflammatory cytokines.
Research has found that GHK-Cu inhibits iron catalyzed lipid peroxidation which is a crucial part of the cell-damaging process after tissue injury. It also binds to the ferritin channel and blocks the release of oxidative free iron which helps to prevent and treat tissue damage.
In addition to its inflammatory and anti-oxidative action, GHK-Cu also regulates the synthesis of proteins that are involved in the repair of tissue. These proteins include collagen, elastin, proteoglycans, glycosaminoglycans, and decorin; all of which are essential for tissue growth and repair.
During the healing process, it acts as a powerful chemoattractant for mast cells and macrophages that promote the release of growth factors that are critical for tissue recovery. In addition, GHK-Cu stimulates the synthesis of proteins that increase the proliferation of fibroblasts and keratinocytes. It increases nerve outgrowth, blood vessel growth, and hair follicle size.
GHK-Cu is especially useful as an adjunctive therapy in the treatment of LPS induced ALI. It can reduce immune cell infiltration and total protein levels in BALF, a key indicator of inflammation, and reduce LPS-induced lung fibrosis.