GHRP is a peptide that stimulates the body to produce growth hormone. It is listed on the World Anti-Doping Agency’s Prohibited List. This supplement can be taken orally, and may also be administered intravenously. Proper use of this substance is essential for its safety and effectiveness.
Synthetic GHRP is a potent hepatoprotector, and it attenuates the inflammatory response orchestrated by liver resident macrophages. In one study, a 15-daily injection of synthetic GHRP reduced circulating levels of IL-6. Furthermore, it decreased nitrite/nitrate release from peritoneal macrophages.
Moreover, GHRP has potential to alleviate a variety of cardiac pathologies. It prevents cardiac cell death, induces cardiac recovery, and attenuates systemic effects. In animal experiments, GHRP is found to reduce mortality and improve long-term outcomes. These benefits have led researchers to study the potential of GHRP as a cardioprotectant.
GHRP is not only useful in cardiovascular health, but is also useful in treating cancer-associated anorexia-cachexia syndrome. While the mechanistic basis for this disorder is still not fully understood, it represents a major barrier to successful chemotherapy. In a rodent model of cancer-bearing-chemotherapy, GHRP-2 administration increased food intake and prolonged median survival time. Such findings suggest the potential of synthetic GHRP to improve quality of life in cancer patients, and may also help counteract catabolic states in other medical conditions.
GHRP-6 has shown promising results in several studies. It has been shown that exogenously administered GHRP can reduce the inflammatory infiltration of mononuclear basophilic round cells. In addition, GHRP-6 has also been shown to improve wound healing. This effect has been noted after 24 hours after the initial administration and persisted until the end of the experiment.