How to Use Copper Complex Peptide to Reduce Fine Lines and Wrinkles

Glycyl-L-Histidine-L-Lysine, or more commonly known as copper complex peptide, is a naturally occurring copper-binding tripeptide that occurs in our bodies—specifically in our blood plasma, saliva, and urine. While the cosmetic versions used in skin and hair products are synthetic, they’re able to mimic the signals our body sends to the epidermis via natural peptides (like, for example, those that help reduce fine lines). It’s also been proven to promote collagen and elastin production, thus reducing the look of fine lines and wrinkles.

“Copper peptides are antioxidants and are thought to stimulate collagen and elastin, which can soften the appearance of fine lines,” says celebrity facialist Joanna Vargas. They’re also thought to be effective for minimizing brown spots and pigmentation, and help boost hydration. “But because copper can oxidize vitamin C, it’s best not to use them in tandem with any retinol or chemical exfoliants,” Mudgil warns.

This formula from 5th Avenue Aesthetics has a whole army of age-fighting ingredients, including blue copper peptides, Greek saffron, niacinamide, and an AHA blend. Combined, they visibly firm the face and erase fine lines.

The copper peptides in this cream are boosted with a patented DNA complex to recognize and eliminate free radicals, which can cause hyperpigmentation. It also has a healthy dose of vegan-friendly squalane to hydrate and ashwagandha to improve skin’s stress response.

This concentrate is made with a trio of anti-aging ingredients—including blue copper peptides and six other peptides and an AHA blend—to target fine lines around the eyes and forehead. It’s also infused with hyaluronic acid to plump the skin.


If you are interested in consuming peptides, it is imperative to consult a medical professional! If any action is taken as a result of this content, we cannot be held liable for any damages. Click on the icon to learn more about why a medical consultation is mandatory!

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