During his extensive research on longevity, professor and gerontologist Vladimir Khavinson extracted a natural peptide from pineal glands of calves. He subsequently synthesized it to create epithalon, a dietary supplement that has shown remarkable results in promoting healthy longevity.
The peptide epithalon stimulates the production of telomerase, which protects the ends of DNA chromosomes known as telomeres, from breaking down over time and thus helps cells continue to function, even in old age. It also has anti-aging properties, and has been shown to decrease the accumulation of oxidative stress in the cell. It has been found to increase night release of melatonin in the pineal gland, and it has restored circadian rhythm in people with pineal gland dysfunction.
In addition, the peptide epithalon significantly reduces the development of spontaneous and chemically-induced carcinogenesis in mice. It acts as a potent antioxidant, decreasing lipid peroxidation and stimulating the activity of CuZn superoxide dismutase. Its anti-cancer effects have been confirmed in a number of experiments. It prevents the spread of tumors in experimental animals, increases lymph flow and targeted death of harmful/useless cells (apoptosis) and reduces the maximum size of a tumor.
Furthermore, the peptide epithalon stimulates genes such as CD5, IL-2 and MMP2, which play a role in the immune system and maintenance of the extracellular matrix in tissues like skin. It also activates fibroblasts, which are important in tissue repair after injury or typical day-to-day stress. This suggests that peptide epithalon may be very beneficial in preventing and treating cancer, as well as improving the overall quality of life in humans.