Thymosin alpha 1 is a peptide hormone naturally produced in the thymus gland, an important part of your immune system that teaches your body to fight harmful bacteria, fungi and viruses. This peptide is able to stimulate T-cells, increase immune function and promote the production of new immune cells. It is also capable of suppressing the proliferation and maturation of cancer cells as well as inhibiting viral replication and inhibiting oxidative stress. It has a unique ability to stimulate the production of antibodies, enhance T-cell response and inhibit immunosuppression by decreasing the production of inflammatory mediators such as IL-1
Studies indicate that thymosin alpha 1 may be effective in the treatment of many autoimmune disorders, including psoriatic arthritis (a chronic disease characterized by rash, nail and joint problems), rheumatoid arthritis, lupus erythematosus, fibromyalgia, and inflammatory myopathies such as polymyositis, dermatomyositis and vasculitis. Thymosin alpha 1 can be given in the form of an injection and is generally very well tolerated with few side effects.
It is a 28-amino acid fragment of a 113-amino acid precursor peptide, prothymosin a-1, and has been shown to restore immune function in animals that have had their thymus glands removed. Thymosin alpha-1 is able to stimulate T-cells, encourage the production of new immune cells, and inhibit the proliferation and maturation of cancer cells as it possesses potent antiviral properties.
It has been used to treat hepatitis C and other viral diseases, malignant melanoma, hepatocellular carcinoma, drug-resistant tuberculosis, Di George’s syndrome, and other chronic cancers. It can also be beneficial for patients undergoing chemotherapy, as it helps reduce the side effects of chemotherapies, such as nausea and vomiting, fatigue, and gastrointestinal disturbances.