Thymosin b4 is an important peptide in the body that promotes tissue repair.
It also inhibits the growth of inflammatory cells in the body and strengthens the immune system. This is why it is often used in the treatment of HIV, AIDS, colds, and other illnesses.
TB4 prolongs cardiac regeneration in mammals and reduces cerebral ischemia/reperfusion injury (26). It reduces apoptosis in oxygen-glucose deprivation and reoxygenation (OGD/R) cells by increasing glucose-regulated protein 78 and downregulating C/EBP homologous protein and caspase-12. In a similar study, Tb4 improved glucose intolerance, reduced insulin resistance, and ameliorated hyperglycemia-induced renal damage in diabetic mice.
Thymosin b4 stimulates vascularization in wounds and prevents collagen degradation at the site of injury. This peptide attracts stem progenitor cells to the area of injury, which create new blood vessels and initiate tissue regeneration and growth.
In addition, it helps increase cell survival, reduces scar formation, and promotes hair growth. This peptide is often prescribed to patients suffering from inflammation, wound healing, and tissue regeneration after surgery.
It is a 43-amino acid, 5kDa polypeptide that is found naturally in the human body. It is present in most blood cells, cerebrospinal fluid, and tears.
Tb4 binds and sequesters actin, which is the primary component of cell structure and movement. It enables cellular processes such as chemotaxis, phagocytosis, and cytokinesis.
Tb4 is a natural, low molecular weight peptide that is released by platelets and macrophages following injury. It binds to monomeric actin, preventing it from polymerizing into filamentous actin. This prevents the development of fibrosis, which is the formation of scar tissue.