Pt 141 is the generic name for a drug called bremelanotide, which is currently FDA-approved for use as a libido treatment in women with hyperactive sexual desire disorder (HSDD) and will soon be sold under the brand name Vyleesi. PT-141 is an injectable melanocortin receptor agonist that works by binding to MC4R in the brain and activating pathways involved in sexual arousal, pleasure, and motivation. It also stimulates a release of dopamine in the hypothalamus, which helps boost sex drive.
While PT-141 can be used on its own to treat sex drive problems, it is often combined with PDE5 inhibitors like Viagra to improve erectile dysfunction. In one small trial, a combination of PT-141 and sildenafil (Viagra) improved the number of men with ED who were able to achieve an erection during sex by around a third.
Unlike many other ED treatments, PT-141 is a quick-acting medication that can help you increase your sex drive and erectile function within minutes to hours of a dose. It is also a safe and effective treatment for most patients.
However, PT-141 can cause side effects in some people. These can include headache, nausea, blurry vision, dizziness, and vomiting. It is important to talk to your doctor about the possible side effects of PT-141 and how they may affect you before starting treatment. Taking your medicine exactly as instructed by your doctor can help reduce the risk of these side effects. If you are experiencing these or other serious side effects, contact your doctor immediately.